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fer 1  (MedChemExpress)


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    Structured Review

    MedChemExpress fer 1
    Fer 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 2422 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ferrostatin+1+fer+1/Ferrostatin-1/pm42790127-50-0-1
    Average 99 stars, based on 2422 article reviews
    fer 1 - by Bioz Stars, 2026-10
    99/100 stars

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    Related Articles

    other:

    Article Title: A novel HDAC1-Hcy/Glu-ferroptosis axis underlies valproic acid-induced hepatic steatosis.
    Article Snippet: Valproic acid (VPA), a widely used antiepileptic drug, often induces hepatic steatosis during long-term treatment, though the underlying mechanisms remain incompletely understood.. In our study, epileptic patients with abnormal liver function exhibited significantly elevated levels of homocysteine (Hcy) and glutamate (Glu) compared to those with normal liver function.. Moreover, Hcy and Glu levels were positively correlated with markers of lipid accumulation and oxidative stress.

    Article Title: Pirfenidone Sensitizes Hepatic Stellate Cells to Ferroptosis by Reprogramming Glutamine and Serine Metabolism for GSH Depletion
    Article Snippet: Pirfenidone (PFD), erastin (ERA), and ferrostatin-1 (Fer-1) were purchased from MedChemExpress (Sollentuna, Sweden).

    Article Title: Chrysin reshapes ferroptosis sensitivity to reverse nickel refining fumes-induced lung injury via the miR-210/ANGPTL4 signaling axis mediated by the PHD1/HIF-1α pathway.
    Article Snippet: Chrysin (purity: 99.85%, CAS No. 480-40-0), ferrostatin-1 (fer-1) (purity: 99.71%, CAS No. 347174–05–4), and erastin (purity: 99.62%, CAS No. 571203–78–6) were sourced from MedChemExpress in MCE (China) Medchemexpress Co., Ltd.

    Inhibition:

    Article Title: Targeting the CTBP1–CETP axis overcomes ferroptosis resistance in non‐small cell lung cancer by altering lipid accumulation
    Article Snippet: .. For experiments involving ferroptosis inhibition, A549 and H1299 cells were pre‐treated with ferrostatin‐1 (Fer‐1) (MedChemExpress) at 2 μM. ..

    Incubation:

    Article Title: NUPR1 and LCN2: Potential Therapeutic Targets for Colorectal Cancer Via Modulating Cell Viability, Migration, and Ferroptosis-Related Pathways.
    Article Snippet: Nuclear protein 1 (NUPR1) is a small, highly basic transcriptional regulator that is involved in regulating a variety of cellular processes.. However, its role in colorectal cancer (CRC) remains uncertain.. This study aimed to elucidate the NUPR1 role in CRC progression and to explore its downstream mechanism.



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    MedChemExpress ferrostatin 1 fer 1
    MAG induced ferroptosis in TNBC cells (A) Intracellular Fe 2+ levels in MAG-treated TNBC cells detected using the FerroOrange probe (B,C) Measurement of LPO and GSH levels in TNBC cells following MAG treatment (D) Protein expression levels of SLC7A11, GPX4, and DMT1 in MAG-treated TNBC cells (E) The morphological characteristics was observed by TEM after treatment with MAG (40 μM) for 24 h (F–I) Relative levels of Fe 2+ , LPO, GSH, and ROS in MDA-MB-231 cells following 2 h pretreatment <t>with</t> <t>Fer-1</t> or DFO, followed by MAG exposure (J) Western blotting of GPX4, SLC7A11, and DMT1 expression in TNBC cells pretreated with or without Fer-1 or DFO for 2 h, followed by MAG for 24 h * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.
    Ferrostatin 1 Fer 1, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ferrostatin+1+fer+1/Ferrostatin-1/pmc13473434-37-0-8
    Average 99 stars, based on 1 article reviews
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    Image Search Results


    MAG induced ferroptosis in TNBC cells (A) Intracellular Fe 2+ levels in MAG-treated TNBC cells detected using the FerroOrange probe (B,C) Measurement of LPO and GSH levels in TNBC cells following MAG treatment (D) Protein expression levels of SLC7A11, GPX4, and DMT1 in MAG-treated TNBC cells (E) The morphological characteristics was observed by TEM after treatment with MAG (40 μM) for 24 h (F–I) Relative levels of Fe 2+ , LPO, GSH, and ROS in MDA-MB-231 cells following 2 h pretreatment with Fer-1 or DFO, followed by MAG exposure (J) Western blotting of GPX4, SLC7A11, and DMT1 expression in TNBC cells pretreated with or without Fer-1 or DFO for 2 h, followed by MAG for 24 h * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.

    Journal: Frontiers in Pharmacology

    Article Title: Magnolol triggers ferroptosis in triple-negative breast cancer through modulation of the ETS2/SLC7A11/GPX4 signaling axis

    doi: 10.3389/fphar.2026.1876648

    Figure Lengend Snippet: MAG induced ferroptosis in TNBC cells (A) Intracellular Fe 2+ levels in MAG-treated TNBC cells detected using the FerroOrange probe (B,C) Measurement of LPO and GSH levels in TNBC cells following MAG treatment (D) Protein expression levels of SLC7A11, GPX4, and DMT1 in MAG-treated TNBC cells (E) The morphological characteristics was observed by TEM after treatment with MAG (40 μM) for 24 h (F–I) Relative levels of Fe 2+ , LPO, GSH, and ROS in MDA-MB-231 cells following 2 h pretreatment with Fer-1 or DFO, followed by MAG exposure (J) Western blotting of GPX4, SLC7A11, and DMT1 expression in TNBC cells pretreated with or without Fer-1 or DFO for 2 h, followed by MAG for 24 h * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001.

    Article Snippet: Ferrostatin-1 (Fer-1) and deferoxamine (DFO) were purchased from MedChemExpress (Shanghai, China).

    Techniques: Expressing, Western Blot